Effect of Vitamin D on Functionality of endothelial Colony forming cells in Coronary artery disease patients

Author : MADHUBALA M

Abstract : Coronary artery disease (CAD) is a leading cause of mortality worldwide and is characterized by endothelial dysfunction and impaired vascular repair. Endothelial colony-forming cells (ECFCs), a proliferative subset of progenitor cells, are vital for vasculogenesis and endothelial repair. In patients with CAD, ECFCs show reduced proliferative and angiogenic potential. Vitamin D, a secosteroid hormone with cardiovascular protective effects, modulates endothelial function via vitamin D receptor (VDR). This study aimed to evaluate whether vitamin D could restore the functional capacity of ECFCs from patients with CAD

Keywords : Coronary artery disease (CAD), Endothelial repair, Endothelial colony-forming cells (ECFCs), Vitamin D, VDR (Vitamin D Receptor)

Conference Name : International Conference on Nutritional Biochemistry, Obesity and Food Science (ICNBOFS-26)

Conference Place : Coimbatore, India

Conference Date : 15th Feb 2026