Effects of dietary heat-inactivated Lactobacillus paracasei postbiotic on growth performance, non-specific immune response and resistance against pathogens in white shrimp (Penaeus vannamei)

Author : Ta-Jeng Yang

Abstract : High-density breeding of white shrimp has led to severe disease outbreaks, such as White Spot Syndrome Virus (WSSV) and Early Mortality Syndrome (EMS), causing significant economic losses. This study investigated the effects of supplementing shrimp diets with a heat-inactivated postbiotic, Lactobacillus paracasei RM-081, to enhance growth and disease resistance. Shrimp were fed diets containing 0, 106, 107, or 108 CFU/g of RM-081 for eight weeks. Results indicated that the 107 CFU/g group achieved the best growth performance (1244.55% weight gain) and showed significantly increased total haemocyte counts and upregulated immune-related genes. Furthermore, the 107 and 108 CFU/g groups exhibited the highest survival rates against Vibrio parahaemolyticus and delayed mortality when challenged with WSSV. In conclusion, supplementing feed with 107 CFU/g of RM-081 effectively promotes growth, boosts nonspecific immunity, and enhances disease resistance in white shrimp

Keywords : Penaeus vannamei, Postbiotic, Innate immunity, Vibrio parahaemolyticus, White-spot syndrome virus (WSSV), heat-inactivated Lactobacillus paracasei

Conference Name : International Conference on Biotechnology Applications in Aquaculture (ICBTAA-26)

Conference Place : Virtrual, Nagoya, Japan

Conference Date : 30th Jun 2026